منابع مشابه
Turning off Neurotransmitters
The historic discovery that the catecholamine neurotransmitters of the sympathetic nervous system, norepinephrine and epinephrine, are inactivated through their reuptake by presynaptic nerve terminals provided new insights into neurotransmitter action and paved the way for the development of modern antidepressant drugs.
متن کاملTurning me on, turning me off
Interactive graphics are an effective way of communication and information delivery, especially for complex domains. However, domain experts are rarely aware of the potentials of interactive visual displays and which interaction principles can be in charge for communication and teaching purposes. In this paper we extend a pattern language for interactive information graphics and present four pa...
متن کاملTurning Online Ciphers Off
CAESAR has caused a heated discussion regarding the merits of one-pass encryption and online ciphers. The latter is a keyed, length preserving function which outputs ciphertext blocks as soon as the respective plaintext block is received. The immediacy of an online cipher gives a clear performance advantage, yet it comes at a price. Since ciphertext blocks cannot depend on later plaintext block...
متن کاملRevisiting Turning Online Cipher Off
In [1], a class of constructions was defined based on layers of secure online ciphers interleaved with simple mixing layers (like reversing and block-shifting). Here we show that an SPRP construction proposed in the work cited is insecure. Howevewr, the same construction is secure under the assumption that the underlying construction is online-but-last ciphers. We include a simpler proof for be...
متن کاملmTORC1: Turning Off Is Just as Important as Turning On
mTORC1 is activated primarily on the lysosome. Menon et al. and Demetriades et al. show that mTORC1 deactivation on the lysosome is determined by recruitment of its negative regulator, the tumor suppressor complex TSC1-TSC2. These reports highlight the importance of subcellular localization in the regulation of mTORC1.
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ژورنال
عنوان ژورنال: Cell
سال: 2006
ISSN: 0092-8674
DOI: 10.1016/j.cell.2006.03.023